British Society of Human Genetics 2010 Conference (Sep 8)
September 8, 2010
Visit infoQuant at the British Society of Human Genetics conference in Warwick, UK, September 6-8, 2010. Explore the latest in array CGH software for clinical and diagnostic copy number analysis.
Please visit a seminar given at BSHG by Rodger Palmer of the Great Ormond Street Hospital jointly with infoQuant:
An approach to the analysis of aCGH data from multiplex microarray platforms in a clinical laboratory setting using the infoQuant "CGH Fusion" and "oneClickCGH" software packages.
Rodger Palmer1 and Anton Petrov2
1Regional Cytogenetics Laboratory, North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London. 2infoQuant Ltd, Suite 86, Naxos Building, London.
The development of aCGH platforms with multiple arrays on a single slide has resulted in significant cost savings and made the use of aCGH as a viable first line test a realistic possibility in clinical cytogenetics laboratories. While the emergence of these array platforms has allowed the streamlining of the laboratory work associated with aCGH there is considerable scope for streamlining data processing and analysis. The use of software which enables the batch processing and documentation of both the array data and sample information is essential for the effective use of this technology in a clinical setting. infoQuant "CGH Fusion" and "oneClickCGH" have been in use in the North East Thames Regional Cytogenetics Laboratory since January 2010 and have been used for the analysis of over 500 samples. This presentation will demonstrate how this software is currently being used for the analysis of data from the Nimblegen 12x135K microarray to offer aCGH as a first line test for patients with dysmorphic features and developmental delay.
